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Using isolated hepatocytes, our study establishes an authentic human model for MMA that recapitulates the known molecular features of the disorder, such as depletion of TCA cycle intermediates and accumulation of metabolites proximal to the impaired enzymatic activity

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What to Know The Centers for Disease Control and Prevention has confirmed the link between COVID-19 and a rare, potentially deadly syndrome in children The syndrome has now been reported in nearly half the nation's states, including New York, New Jersey and Connecticut