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The first step in this transport process involves binding of the cationic aminoglycoside to apical membrane receptors, thought to be anionic phospholipids such as phosphatidylinositol (Sastrasinh et al., 1982)

As direct technical positive controls for DNA strand break induction, the liver models were treated for 1 h with ethyl methanesulfonate (EMS

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doi:10.1080/00016489.2021.1957145