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The first step in this transport process involves binding of the cationic aminoglycoside to apical membrane receptors, thought to be anionic phospholipids such as phosphatidylinositol (Sastrasinh et al., 1982)

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As direct technical positive controls for DNA strand break induction, the liver models were treated for 1 h with ethyl methanesulfonate (EMS

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doi:10.1080/00016489.2021.1957145

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