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Acknowledgments The authors would like to thank Aouatef Bellamine, for her help with study management and Suzanne Morris, at Concrete Medical Writing, LLC, for providing medical writing support (funded by Lonza)

Furthermore, the mood-enhancing properties of ALC, attributed to its potential to balance brain chemicals, make it a valuable supplement for improving overall well-being

This condition cannot be fully compensated by conventional nutritional support, resulting in progressive functional defects in these patients

As depression has been previously shown to be associated with changes in neurometabolites, mood and anxiety ratings were performed: the Beck Depression Inventory II (BDI-II) [30] for mood, the Spielberger State Anxiety Inventory (STAI) for anxiety [31]