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Evaluation of the effect of lactobacillus planetarium probiotics produced from broad bean seed in prevention of helicobacter pylori in stomach tissue of C57BL/6 mice

Once the body is in oxidative stress, or if there are a large number of electrophiles or cytotoxic agents, Nrf2 is released from the Keap1 binding site and rapidly transferred to the nucleus, subsequently interacting with the antioxidant response element (ARE) in the promoter region of the target gene and then activates the transcriptional pathway to balance oxidative stress and maintain cellular redox homeostasis (Zhang, 2006)