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Scopolamines negative effect on memory and attention was greater with injectable (e.g., intramuscular, intravenous, and subcutaneous) compared to non-injectable routes of administration (e.g., intranasal, oral, and transdermal)

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Phase 2 clinical trial data published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated mean body weight reductions of up to approximately 24% over 48 weeks in adults with obesity a notable finding, though long-term durability data and head-to-head comparisons with other treatments are not yet available

According to the UK SmPC, the inactive ingredients (excipients) in Mounjaro include sodium chloride, sodium phosphate dibasic heptahydrate, sodium hydroxide and hydrochloric acid (for pH adjustment), and water for injections