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Pegloticase may be especially useful in patients with very large collections of uric acid (tophi), especially if these are draining to the skin
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[DOI] [PubMed] [Google Scholar] 25.Gojkovic S., Krezic I., Vrdoljak B., Malekinusic D., Barisic I., Petrovic A., Horvat Pavlov K., Kolovrat M., Duzel A., Knezevic M., et al
Choline is converted to betaine, and betaine acts as a methyl-group donor in the methionine cycle running through the liver and kidneys
