melanotan 2 dopamine The Melanocortin System: A Promising Target for the Development of New Antidepressant Drugs Melanotan 2 - Unit Peptides

10.1001/archneur.1994.00540190110024 195 SaifM

Sun's influence on melanin synthesis Solar radiation affects skin pigmentation differently depending on the type of UV rays: Immediate pigmentation UVA radiation (315-400 nm) Causes immediate skin darkening within 5-10 minutes Effect lasts from several minutes to several days Does not increase new melanin production Works through photochemical reactions causing darkening and redistribution of existing melanin Delayed pigmentation UVB radiation (280-315 nm) Stimulates new melanin synthesis Effect appears 2-3 days after exposure Lasts several weeks Predominantly stimulates eumelanin production Can cause sunburn with excessive exposure Chronic sun exposure increases overall melanin levels and provides additional natural protection from UV radiation

The number had in fact been invented by Holmes to help salvage his waning image

Additional colour coding: Caspase-9 (light orange), caspase-3 (salmon pink)