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Mechanistic descriptions are based on well-established biochemical pathways and are presented for educational purposes only
doi: 10.2147/PHMT.S389105

The Organ Index Refers to the Ratio of the Weight of Animal Organs to Body Weight Any factor that affects the organ weight will cause this value to change

When ROS levels exceed those of antioxidant defenses, there is an aberrant increase in free radical generation resulting in mitochondrial damage and leading to oxidative stress and subsequently this increased stress can reduce ETC activity (Figure 2)
