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Testosterone replacement therapy (TRT) can reduce sperm production and temporarily impact fertility in some men, making it important to discuss family planning goals with a healthcare provider before starting treatment
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163 These suggest that the ferroxidase activity of ceruloplasmin is diminished by copper deficiency, which then causes the accumulation of iron and promotes the development of PD

A reaction that might be mild and manageable at conservative doses becomes more significant at intensive levels
