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The research priorities are clear: Phase I safety trials in healthy volunteers must be completed, followed by Phase II efficacy trials for specific conditions if safety is confirmed

In addition to these direct tumor suppressive effects on pre-malignant cells, TGF- acts as an indirect tumor suppressor by preventing inflammatory responses that cause cancer predisposition
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Hence, Bifidobacterium improves intestinal barrier function through the downregulation of both Zonulin and inflammatory cytokines