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Description
The activated lipase breaks down stored triglycerides into free fatty acids that can be released into the bloodstream and oxidized for energy
Based on the structure of Tepotinib, we introduced chiral restriction conformation and hydrogen isotope deuterium to improve its metabolic stability, and synthesized a new structure of small molecule inhibitor 1D228
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Such properties highlight DSIPs potential role as a regulator of oxidative balance at a fundamental cellular level
