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4 Alcohol and ER stress Cell damage can be caused not only by oxidative stress but also by ER stress, which acts as a secondary hit model for disease progression (73)

Arts IS, Gennaris A, Collet J-F

Release of Ca2+ from the endoplasmic reticulum and its subsequent influx into mitochondria trigger celastrol-induced paraptosis in cancer cells
Diversity between the systems appears to have evolved through use of novel proteins, and matching of protein components between translocation machineries 8
