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Chief cells within the epithelium of the stomach secrete pepsinogen, a digestive pro-enzyme
However, the largest 24-week trial with 536 participants failed to show statistically significant weight loss, which led to development termination
FDA warnings and labeling also address psychiatric and neurologic effects, serious blood sugar disturbances, increased risk of aortic aneurysm or dissection in certain patients, and ciprofloxacins inhibition of CYP1A2
