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In agreement with this, higher levels of the catechol oxidative metabolite 3-OCH 3 -APAP-Glu were also observed in PHH compared to HRG cells
Additionally, IL-5 inhibitors have minimal impact on lung function metrics such as FEV 1 , and some studies have even observed no improvement or a decline in lung function, suggesting they may struggle to reverse the core pathological change of airflow limitation
however, individual responses can vary significantly due to genetic factors influencing metabolism rates
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