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[910] However, when vitamin D is compounded at appropriate concentrations and combined thoughtfully with other supportive ingredients, it may help strengthen the skin barrier and reduce inflammation without the concerns seen in older formulations

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It is relevant to note that, in patients with upper gastrointestinal symptoms, there are about 25% of patients with delayed gastric emptying, about 25% with impaired gastric accommodation, and about 25% with the combination of both gastric motor dysfunctions (Park et al., 2017