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This hyperresponsive immune phenotype persists in allergic adolescents, marked by increased circulating dendritic/monocyte populations and elevated secretion of IL-6, IL-1, and TNF- upon LPS challenge (150)

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Here we argue that its role as redox pair with oxidised glutathione (GSSG) is pivotal with regard to controlling the electrical or redox gradient across the mitochondrial inner-membrane

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