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Description
H 2 O 2 does not react with thiols

Oxidative stress caused by a variety of agents and drug-resistant tumor cell lines are two conditions associated with increased cell GSH levels, GCL activity, GCLC mRNA levels and GCLC gene transcription (Mulcahy et al., 1994a

Given that A42 peptide oligomers are resident in the lipid bilayer (17, 18, 21, 120), coupled with the requirement that a lipid-resident free radical is necessary to initiate the processes of lipid peroxidation (free radicals outside the bilayer would be too reactive to survive entering the bilayer in the first place), consistent with the location of the Met35 residue of A42, we posit that the sulfuranyl free radical of A42 is the initiator of lipid peroxidation associated with this peptide (FIGURE 8)

This makes them exceedingly simple and convenient to use
