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Mitochondria-targeted analogues of metformin exhibit enhanced antiproliferative and radiosensitizing effects in pancreatic cancer cells
This combination strategy effectively reduces cell viability and induces apoptosis, thereby further corroborating the feasibility of integrating metabolic intervention with conventional chemotherapy (112)
BCL2 inhibition by BH3 mimetic can trigger ROS generation to amplify apoptosis in cancer cells [116]
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