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[1] [3] Some medications, such as chloramphenicol, may interact with B12 therapy
However, fasting can lead to fluctuations in nutrient availability, raising concerns about how external supplementation may impact the body's natural processes
Free Radical Biol Med 1(87):14 Orian L et al (2018) The catalytic mechanism of glutathione peroxidases in Glutathione

Though high pressure processing is generally considered to lead to better preservation of vitamins, compared with thermal treatment, this obviously is not the case for folates 106