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All the participating subjects provided their written consent (for medical investigations, blood samples, monitoring)

These findings suggest that hexarelin protects in vivo cardiomyocytes from I/R injury partly by modification of the IL-1 signaling pathway through the activation of cardiac GHSR1a receptors. Apart from supporting the survival of heart muscle cells, the peptide Hexarelin may protect the heart from the long-term effects of oxidative stress, especially for people with a past history heart attacks or any cardiac injuries

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