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Description
This creates constant energy demand, leading to a massive influx of oxygen and the production of reactive oxygen species (ROS) that can damage the very cellular machinery that powers the cell
The first and foremost is the liver
In contrast to most other spider venom enzymes, PLDs have been studied in detail because they are medically relevant
To support this, we compiled representative PK data for toxic TCMs listed in the Chinese Pharmacopoeia (ChP), as summarized in Table S1, Additional File 1
