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Interestingly, NECTIN-4 and TROP-2 are highly expressed in normal skin and its appendages, as well as in various skin cancers [128,129,130,131,132,133,134,135], and anti-NECTIN-4 ADC might be a candidate for unresectable skin cancers, including NAM
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HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression
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