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Acknowledgements We thank the Seoul National University Institutional Animal Facility

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3 Drug repurposing 3.1 Significance of drug repurposing Drug repurposing can shorten development times by 57 years, reduce research investment costs by accounting for less than 10% of new compounds, and avoid risks such as a constant weight of generics (Turanli et al., 2021)

Peer review Peer review information Nature Protocols thanks Ilaria Armenia, Stefano Fedeli, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work
