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H3R antagonists such as ciproxifan have also been effective in enhancing alertness and memory [60], alleviating repetitive behavior in VPA-exposed mice [62], and correcting aberrant histamine-modulated neural activity in the cortico-basal ganglia circuitry [63,64] (Figure 1)

Delivery of dual drug loaded lipid based nanoparticles across the bloodbrain barrier impart enhanced neuroprotection in a rotenone induced mouse model of Parkinsons disease

Meringer, M., Reinker, S., Zhang, J

10.1074/jbc.M109.085084 207 WuT
