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The above-mentioned mechanism of the skin-whitening efficacy of topical GSSG and its relationship to GSH are not clear and are no more than speculation

Previous studies have reported that RGSH can inhibit oxidative stress and thus alleviate liver damage (27), and improve renal function in patients by reducing the serum creatinine levels (28)

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Proteins were then denatured for 5 min at 95 C in Laemmli buffer (31 mM Tris pH 6.8
