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10.1038/ncb2422 74 LiuS.PiJ.ZhangQ
Nucleosides Nucleotides Nucleic Acids (2022) 41(2):12336
Thus, all three of the main UA transporters may contribute to the brain concentrations of UA through their action at the blood-brain barrier, although ABCG2 is thought to have the greatest effect, probably acting to remove UA from brain to blood 45
Complementary findings in dietary obesity models have also been reported, where AgRP levels were elevated under hyperphagic conditions and reduced with food restriction, while -MSH and POMC concentrations remained unchanged [60]
