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[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Saccoccia F., Angelucci F., Boumis G., Carotti D., Desiato G.E., Miele A., Bellelli A

Superoxide dismutase is a major superoxide scavenger in humans and converts the superoxide anion to hydrogen peroxide, which is a substrate for catalase and GSH-Px

This oxidative stress is not only involved in the toxicity of xenobiotics but also in the pathophysiology of various ailments like ischaemia reperfusion injury, vascular endothelium, deep injuries, organ dysfunction, shock, inflammation, sepsis, diabetic retinopathy, cancer, cognitive dysfunction, cataract, and heart disease