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Alterations in the gut microbiota cause a defect in the mucus layer that increases the intestinal permeability to pathogens and triggers an immune response, causing intestinal inflammation (Michielan, and DInc, 2015)

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reported a K d of 22 nM for peptide 1 binding to EGFR where the authors studied direct binding of the peptide to the pure EGFR protein 8

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