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Zhang S, Yang Y, Liang Z, Duan W, Yang J, Yan J, et al
When extracellular NAD+ levels in the bloodstream rise above normal, as can happen with high-dose IV infusions, the body may interpret this as trauma within the body, leading to an immune response, and potentially causing inflammation
Up-regulation of renal and vascular nitric oxide synthase in iron-deficiency anemia
Additionally, IAA entry into the brain hampers glycolysis, consequently lowering ATP levels in nerve cells (Sperling et al., 2003
