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Because our bodies cant make EPA or DHA, we have to get them from food or supplements
However, differences in reporting and patient evaluation potentially allow for confounding variables that affecting the presumed correlation between statin use and the development of cholestatic hepatitis
Proposed mechanisms include circulatory disturbances in liver cirrhosis, metabolic and neurohormonal (renin-angiotensin-aldosterone system) dysfunctions, excessive nitric oxide production, oxidative stress, and inflammatory mediators [11, 171]
Blood 114, 40644076 (2009)
