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In adipose models, reduced NNMT activity has been linked with smaller adipocyte size and diminished fat depots, suggesting a potential role for this inhibitor in fat mass modulation under research conditions

While losing some lean mass during aggressive weight loss is expected, this ratio is favorable compared to diet-only approaches where lean mass losses can reach 30-40%

The practical tradeoffs between the two methods come down to time, customization, and cost

What if it is administered to someone who should not be getting them
