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Reduced secretion of gastric acid and pepsin, from the use of H 2 blocker or proton-pump inhibitor (PPI) drugs, can reduce the absorption of protein-bound (dietary) vitamin B 12 , although not of supplemental vitamin B 12
Ng, Journal (Endocrinology, Volume 142, Issue 12, December 2001, Pages 51825189)

the key is consistency to aid adherence
