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& Manns, M

The complement complex C1q is comprised of C1qA, C1qB, and C1qC and facilitates the first step of classical complement pathway activation.[207]

These properties make peptides significant research targets for treating infectious, inflammatory, and tumor diseases of the oral cavity, such as caries, periodontitis, stomatitis, and tumors

Indeed, there is evidence for major changes in expression of the serotonin reuptake transporter and increased expression of mucosal 5-HT in mammals with inflammatory bowel disease and it is possible that endogenous 5-HT is largely responsible for the changes in ENS excitability only in disease states 121,122
