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Description
Overcoming multidrug resistance of cancer cells by direct intranuclear drug delivery using TAT-conjugated mesoporous silica nanoparticles
Subjects were followed for 24 (VISP), 40 (NORVIT), 60 (HOPE-2), 88 (WAFACS), 41 (VITATOPS), or 80 months (SEARCH)
The dose may change based on how the patient responds and their specific health issues
: impairment of DNA methylation maintenance is the main cause of global demethylation in naive embryonic stem cells
