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The review underscores the importance of lactate in tumor progression and provides valuable perspectives on potential therapeutic approaches that target the vulnerability of lactate metabolism, highlighting the Heel of Achilles for cancer treatment

doi: 10.1038/s41593-017-0010-3 187

In Fischer-344 rats, the testes were moderately to markedly atrophic at the two highest doses (400 and 800 mg/kg of body weight per day), with varying degrees of hypospermatogenesis and multinucleated giant cell formation

C.HeckK.JuritschA
