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Statistical Analysis Data were analyzed using GraphPad Prism 8 (GraphPad Software, San Diego, CA, USA)

Numerous studies have shown that NO is a sensitive biomarker of eosinophil-mediated inflammation and that it is positively correlated with other diagnostic markers in bioptates, BAL fluids, and induced sputum (104, 109, 110)

Insulin itself, via the MAPK pathway and through its binding to the IGF receptor, stimulates cell growth at various levels, but for our purposes, we are particularly interested in the stimulation of growth in endothelial cells, vascular smooth muscle cells, and cardiomyocytes [34, 35]

[DOI] [PMC free article] [PubMed] [Google Scholar] 113.Fernandes J., Gupta G.L