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Hence, unlike transport of most other amino acids, where Na + -dependent transporters play the dominant role in the apical side and facilitated diffusion occurs through the basolateral side, cationic amino acids use antiporters in both sides of enterocytes and cells of proximal tubules in the renal cortex [22,23]

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Based on the plethora of symptoms affecting different organs/systems, PASC-affected population could be categorized into four different clusters or sub-phenotypes: Sub-phenotype-1 (33.8%) with cardiac and renal manifestations, Sub-phenotype-2 (32.8%) with respiratory, sleep and anxiety disorders, Sub-phenotype-3 (23.4%) with skeleton-muscular and nervous disorders, and Sub-phenotype-4 (10.1%) with digestive and pulmonary dysfunctions 123,136