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Edited by Dr Gerry Melino Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made

DISCUSSION Vitamin B12 is a water-soluble vitamin that cannot be synthesised by humans

Also, there is no alternative method whereby homocysteine can be remethylated to methionine since betaine-homocysteine methyltransferase is absent in the brain

Pittsburghs annual Light Up Night is a tradition for our community
