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2 Folate supplementation can correct these haematological effects of B12 deficiency but not the neurological complications, which include neuropathies, such as tingling and numbness in the arms and legs, sensory and motor disturbances, including abnormal gait, and cognitive changes

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~20% weight loss at 72 weeks Approved drug entries reflect U.S

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This selectivity is crucial because many methyltransferases play essential roles in neurotransmitter metabolism, gene expression, and protein function

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Consider supplementation if dietary intake seems inadequate

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