glutathione tripeptide containing residue oxidizing agents.. Write the scheme

In vitro experiments on lung cancer cells revealed that L-asparaginase treatment significantly induced autophagy activation in A549 cells, leading to their apoptosis (108)

10.1126/science.abl6618 12 HashemiY

During treatment of pulmonary fibrotic rats with EGCG, the rats exhibited reduced inflammation, alveolar damage, and vascular congestion, which were associated with the membrane-stabilizing and antioxidant properties of EGCG, demonstrating that EGCG can act as a potential anti-fibrotic drug (73)

This regulatory mechanism underscores DJ-1s crucial role in cellular defense against oxidative stress, highlighting its potential as a therapeutic target for neurodegenerative diseases and conditions involving oxidative damage (Wang H