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They facilitate the oxidation of cytosolic NADH, generated in the course of glycolysis because of the mitochondrial inner membrane's inability to transport NADH, but some scientists hypothesized that they are predominantly jumbled in respiration when cells were vegetated on ethanol (Mancebo et al., 2022)

[DOI] [PMC free article] [PubMed] [Google Scholar] 145.Olson ER, Shamhart PE, Naugle JE and Meszaros JG

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These effects are mediated through downstream activation of transcription factors such as c-Fos, c-Jun, and EGR-1, which regulate genes involved in cell cycle progression, extracellular matrix remodeling, and angiogenic signaling [26]