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The ability to improve and maintain NO synthesis, which plays a vital role in vasodilation, is necessary for increased oxygen uptake in skeletal muscle [115]
Apoptosis is a programmed process of cell death for the removal of injured cells, and it can be triggered in open-heart surgery by various factors, including myocardial stretch, increased inflammatory cytokines production, and oxidative stress during cardioplegia that involves myocardial ischemia and reperfusion [20]
Carnitine has been widely recommended as a supplement in cardiovascular disease
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