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Description
E2 catalyzes the transfer of the acetyl group from the lipoate moiety to CoA, forming acetyl-CoA and dihydrolipoate

Pharmacol Rev 1991;43:10942.PubMed 27

Ferreira et al., 2016)

It is also well understood that a slight change in the chemical structure of a drug not only changes the overall three-dimensional structure but also alters its electronic nature as well as physicochemical properties such as solubility, lipophilicity, and ionization potential
