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Importantly, MTNs also receive innervation from nitric oxide synthase-containing fibers and respond electrophysiologically to nitric oxide, suggesting modulation of excitability and synaptic transmission via the nitric oxidecGMP pathway (Pose et al., 2003)

(Milano: Springer), 877891
Such heterogeneity within lesions is not only problematic for scoring degrees of dysplasia in a nevus, but also may lead to missing a diagnosis of melanoma arising within the nevus in some cases
A further family of antioxidants particularly affected by OS and nitrosative stress are the peroxiredoxins (Prxs), which reduce H 2 O 2 (124) and present a redox-regulated chaperone activity
