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Major lifestyle determinants of plasma total homocysteine distribution: the Hordaland Homocysteine Study

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Furthemore, an increased serotonin metabolism was demonstrated by diminished hypothalamic serotonin levels, lowered 5-hydroxytryptamine (5-HT)/tryptophan ratios and elevated 5-hydroxyindoleacetic acid/5-HT ratios, indicating dysregulated serotonergic system (Jia et al., 2024)

This increased expression of SOD1 appears to increase cell proliferation and metastasis, potentially by facilitating cell cycle progression and inhibiting apoptotic processes