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What is the significance of organoid culture

Kikuchi K, Tabuchi K, Inoue S, Yamashita A, Kinouchi S, Hashida R, Iwanaga J, Watanabe K, Tubbs RS, Okawa T, Hiraoka K (2024)
Some people are impossible to please
These mutations lead to inadequate levels of the enzyme, very long-chain acyl-coenzyme A dehydrogenase resulting in the accumulation of long-chain fatty acids and patients are unable to make ketone bodies for energy
