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Serum BDNF as a peripheral biomarker of treatment-resistant depression and the rapid antidepressant response: a comparison of ketamine and ECT

Over 50 years of research and 70+ published studies support its safety at therapeutic doses

Expanding research has broadened epigenetic regulation beyond the nucleus, showing that mitochondrial DNA (mtDNA) also undergoes dynamic modifications, including methylation, which offer fresh insights into bidirectional mitochondrial-nuclear communication

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