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Description
Predrag Sikiric and colleagues at the University of Zagreb first characterized it in 1993
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Among them, genes such as CD14, CD36, CD163, and C5AR1 are canonically expressed in Kupffer cells, while others like CD52 and SCARB2 are enriched in dendritic cells and contribute to antigen processing and immune activation

The magnitude of change in sleep and physical score at 4 weeks was significant between the two groups ( p = 0.000)
