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The main research in this field has been aimed at depleting GSH by a specific inhibition of GCL, a key enzyme of GSH biosynthesis
Curcumin consumption reduced oxidative stress caused by heavy metals, gentamicin, and acetaminophen in rats (Liu et al., 2023
Oxidative stress, primarily due to the accumulation of reactive oxygen species (ROS), impairs endothelial function, reduces NO bioavailability, and promotes vascular dysfunction, which conditions all amount to key mechanisms in ED onset and progression
Variable responses to different treatments, including cisplatin, have been seen from different points of view
