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Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation

In a separate study [64], an attempt was made, by employing the comet assay, to address whether or not the pretreatment with exogenous GSH protects or potentiates the yield of chromosomal damage induced by ionizing radiation

As an important component of regulating metabolism and immune homeostasis, the vagus nerve can regulate WAT content through the central nervous system to control sympathetic peripheral muscle bundles, and can also regulate the release of GSH and NO to enhance antioxidant capacity and prevent ferroptosis (103)

Association between fatigue, peripheral serotonin, and L-carnitine in hypothyroidism and in chronic fatigue syndrome